deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT01946204

A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer (SPARTAN)

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Study of ARN-509 in Men With Non-Metastatic (M0) Castration-Resistant Prostate Cancer

Sponsor: Aragon Pharmaceuticals, Inc.

Conditions Prostatic Neoplasms
Interventions Apalutamide Placebo
Updated 65 times since 2017 Last updated: Jan 15, 2026 Started: Oct 14, 2013 Primary completion: May 19, 2017 Completion: Dec 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01946204, this PHASE3 trial focuses on Prostatic Neoplasms and remains ongoing. Sponsored by Aragon Pharmaceuticals, Inc., it has been updated 65 times since 2013, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshot~Oct 2017 – ~Mar 2018 · 5 months · monthly snapshot~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Jan 2019 · 3 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Jun 2019 · 3 months · monthly snapshot~Jun 2019 – ~Aug 2020 · 14 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

65 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jan 2026 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  4. Nov 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE3

▶ Show 60 earlier versions

  1. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE3

  5. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

  6. Apr 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  7. Mar 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

  8. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE3

  9. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

  10. Nov 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

  11. Oct 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE3

  12. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE3

  13. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  14. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

  15. May 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  16. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE3

  17. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE3

  18. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  19. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

  20. Dec 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE3

  21. Nov 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE3

  22. Oct 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE3

  23. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE3

  24. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE3

  25. Jun 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE3

  26. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE3

  27. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE3

  28. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE3

  29. Feb 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE3

  30. Dec 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

  31. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE3

  32. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE3

  33. Jun 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  34. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

  35. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE3

  36. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  37. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

  38. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE3

  39. Dec 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE3

  40. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE3

  41. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE3

  42. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  43. May 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  44. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE3

  45. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  46. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  47. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE3

  48. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  49. Jun 2019 — Aug 2020 [monthly]

    Active Not Recruiting PHASE3

  50. Mar 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE3

  51. Feb 2019 — Mar 2019 [monthly]

    Active Not Recruiting PHASE3

  52. Jan 2019 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  53. Oct 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE3

  54. Sep 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE3

  55. Jul 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

  56. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE3

  57. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  58. Oct 2017 — Mar 2018 [monthly]

    Active Not Recruiting PHASE3

  59. Feb 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE3

  60. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Oct 2013

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Aragon Pharmaceuticals, Inc.
Data source: Aragon Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

A Coruña, Spain , Aachen, Germany , Aalborg C, Denmark , Abbotsford, Canada , Abilene, United States , Adelaide, Australia , Akita, Japan , Albany, United States , Albuquerque, United States , Alkmaar, Netherlands and 368 more locations