deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03526848

3BNC117 and 10-1074 in ART-treated Individuals

An Open Label, Randomized Study of the Safety and Antiretroviral Activity of 3BNC117 and 10-1074 in HIV-infected Individuals on Combination Antiretroviral Therapy and During Analytical Treatment Interruption.

Sponsor: Montefiore Medical Center

Updated 14 times since 2018 Last updated: Sep 25, 2025 Started: Jun 5, 2018 Primary completion: Sep 30, 2021 Completion: Feb 11, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Human Immunodeficiency Virus and is currently completed. Montefiore Medical Center leads this study, which shows 14 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Jul 2019 · 12 months · monthly snapshot~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Feb 2022 · 11 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Jul 2024 · 28 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2025 · 14 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

14 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Nov 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Mar 2022 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  5. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE1

Show 9 earlier versions
  1. Mar 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  2. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  3. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

    Status: Active Not RecruitingRecruiting

  4. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

  5. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  6. Feb 2020 — May 2020 [monthly]

    Recruiting PHASE1

  7. Jul 2019 — Feb 2020 [monthly]

    Recruiting PHASE1

  8. Jul 2018 — Jul 2019 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  9. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Montefiore Medical Center
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • Ragon Institute of MGH, MIT and Harvard
  • Rockefeller University
Data source: Rockefeller University

For direct contact, visit the study record on ClinicalTrials.gov .