deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT03536143

A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients (GEM-1)

A Phase I/II Study of KB103, a Non-Integrating, Replication-Incompetent HSV Vector Expressing the Human Collagen VII Protein, for the Treatment of Dystrophic Epidermolysis Bullosa (DEB)

Sponsor: Krystal Biotech, Inc.

Updated 9 times since 2018 Last updated: Jan 30, 2023 Started: May 6, 2018 Primary completion: Nov 1, 2019 Completion: Nov 1, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Dystrophic Epidermolysis Bullosa, this trial is completed. The trial is conducted by Krystal Biotech, Inc. and has accumulated 9 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotRecruiting~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshotRecruiting~Feb 2019 – ~Apr 2020 · 14 months · monthly snapshotRecruiting~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotActive Not Recruiting~Oct 2021 – ~Feb 2023 · 16 months · monthly snapshotActive Not Recruiting~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted · Phase: PHASE2PHASE1_PHASE2

  4. Oct 2021 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2

Show 4 earlier versions
  1. Apr 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Feb 2019 — Apr 2020 [monthly]

    Recruiting PHASE2

  3. Nov 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

    Phase: PHASE1_PHASE2PHASE2

  4. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

May 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Krystal Biotech, Inc.
Data source: Krystal Biotech, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations