deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT03587805

Long-term Extension Trial in Subjects With Atopic Dermatitis Who Participated in Previous Tralokinumab Trials - ECZTEND

An Open-label, Single-arm, Multi-centre, Long-term Extension Trial to Evaluate the Safety and Efficacy of Tralokinumab in Subjects With Atopic Dermatitis Who Participated in Previous Tralokinumab Clinical Trials

Sponsor: LEO Pharma

Conditions Atopic Dermatitis
Interventions Tralokinumab
Updated 53 times since 2018 Last updated: Feb 21, 2025 Started: Mar 18, 2018 Primary completion: Jul 3, 2024 Completion: Jul 3, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Atopic Dermatitis and is currently completed. LEO Pharma leads this study, which shows 53 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Aug 2020 · 2 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~May 2021 · 3 months · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshot~Sep 2025 – present · 8 months · monthly snapshot

Change History

53 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Apr 2025 — Sep 2025 [monthly]

    Completed PHASE3

  3. Feb 2025 — Apr 2025 [monthly]

    Completed PHASE3

  4. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

▶ Show 48 earlier versions

  1. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Dec 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE3

  6. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE3

  7. Jun 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE3

  8. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE3

  9. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE3

  10. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE3

  11. Feb 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE3

  12. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

  13. Dec 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE3

  14. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE3

  15. Sep 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE3

  16. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  17. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE3

  18. May 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

  19. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE3

  20. Dec 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  21. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE3

    Status: Enrolling By Invitation → Active Not Recruiting

  22. Oct 2021 — Nov 2021 [monthly]

    Enrolling By Invitation PHASE3

  23. Sep 2021 — Oct 2021 [monthly]

    Enrolling By Invitation PHASE3

  24. Jun 2021 — Sep 2021 [monthly]

    Enrolling By Invitation PHASE3

  25. May 2021 — Jun 2021 [monthly]

    Enrolling By Invitation PHASE3

  26. Feb 2021 — May 2021 [monthly]

    Enrolling By Invitation PHASE3

  27. Jan 2021 — Feb 2021 [monthly]

    Enrolling By Invitation PHASE3

  28. Sep 2020 — Jan 2021 [monthly]

    Enrolling By Invitation PHASE3

  29. Aug 2020 — Sep 2020 [monthly]

    Enrolling By Invitation PHASE3

  30. Jun 2020 — Aug 2020 [monthly]

    Enrolling By Invitation PHASE3

    Status: Recruiting → Enrolling By Invitation

  31. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  32. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  33. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  34. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  35. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  36. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  37. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  38. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  39. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  40. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  41. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  42. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  43. Jan 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  44. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  45. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  46. Oct 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE3

  47. Sep 2018 — Oct 2018 [monthly]

    Not Yet Recruiting PHASE3

  48. Aug 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Mar 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • LEO Pharma
Data source: LEO Pharma

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Ajax, Canada , Albany, United States , Alicante, Spain , Ann Arbor, United States , Asahikawa, Japan , Augsburg, Germany , Austin, United States , Bad Bentheim, Germany , Badalona, Spain and 227 more locations