deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03600714

Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda Interferon

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions Hepatitis D Liver Disease
Interventions Lonafarnib Peg-interferon lambda Ritonavir
Updated 29 times since 2018 Last updated: Dec 6, 2021 Started: Aug 1, 2018 Primary completion: Feb 5, 2020 Completion: Aug 11, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Hepatitis D and Liver Disease and is currently completed. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) leads this study, which shows 29 recorded versions since 2018 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Jan 2019 · 3 months · monthly snapshot~Jan 2019 – ~Jun 2019 · 5 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshot~Jan 2022 – ~Jul 2024 · 30 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshot

Change History

29 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2022 — Jul 2024 [monthly]

    Completed PHASE2

  4. Sep 2021 — Jan 2022 [monthly]

    Completed PHASE2

  5. Jun 2021 — Sep 2021 [monthly]

    Completed PHASE2

▶ Show 24 earlier versions

  1. May 2021 — Jun 2021 [monthly]

    Completed PHASE2

  2. Apr 2021 — May 2021 [monthly]

    Completed PHASE2

  3. Jan 2021 — Apr 2021 [monthly]

    Completed PHASE2

  4. Dec 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  5. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE2

  6. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  7. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE2

  8. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  9. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  10. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

  11. Apr 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  12. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  13. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  14. Dec 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  15. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  16. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  17. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  18. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  19. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  20. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  21. Jan 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  22. Oct 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  23. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  24. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations