deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03667690

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

A Phase 3, Multicenter, Randomized, Double-blind Study of the Efficacy and Safety of Rezafungin for Injection vs. Intravenous Caspofungin Followed by Oral Fluconazole Step Down in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis

Sponsor: Cidara Therapeutics Inc.

Conditions Candidemia Fungal Infection Invasive Candidiases Mycoses
Interventions Caspofungin Fluconazole Rezafungin for Injection intravenous placebo oral placebo
Updated 32 times since 2018 Last updated: Dec 13, 2022 Started: Oct 7, 2018 Primary completion: Oct 7, 2021 Completion: Oct 7, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Candidemia and Fungal Infection, this trial is completed. The trial is conducted by Cidara Therapeutics Inc. and has accumulated 32 data snapshots since 2018. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Mar 2019 · 4 months · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Mar 2022 · 6 months · monthly snapshot~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshot~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 8 months · monthly snapshot

Change History

32 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Mar 2022 — Feb 2023 [monthly]

    Completed PHASE3

    Status: Active Not Recruiting → Completed

▶ Show 27 earlier versions

  1. Sep 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  2. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  3. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  4. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  5. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  6. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  7. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  8. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  9. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  10. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  11. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  12. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  13. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

  14. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  15. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  16. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  17. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  18. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  19. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  20. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  21. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  22. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  23. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  24. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  25. Mar 2019 — May 2019 [monthly]

    Recruiting PHASE3

  26. Nov 2018 — Mar 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  27. Oct 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cidara Therapeutics Inc.
Data source: Cidara Therapeutics Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amiens, France , Ankara, Turkey (Türkiye) , Argenteuil, France , Armenia, Colombia , Athens, Greece , Atlanta, United States , Augusta, United States , Badalona, Spain , Baltimore, United States , Bangkok, Thailand and 87 more locations