Unknown PHASE3 INTERVENTIONAL 3-arm NCT03687268

Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation (Naxos)

Randomised, Double-blind, Placebo-controlled, Parallel-group, Multi-centre, Phase III Trial to Investigate the Efficacy, Safety and Tolerability of Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation

Sponsor: Develco Pharma Schweiz AG

Conditions Opioid-Induced Constipation

Interventions Naloxone HCl PR tablets Placebo Oral Tablet

Updated 6 times since 2018 Last updated: Sep 27, 2018 Started: Jul 31, 2017 Primary completion: Nov 30, 2019 Completion: Dec 31, 2019

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Opioid-Induced Constipation, this trial is ongoing. The trial is conducted by Develco Pharma Schweiz AG and has accumulated 6 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Unknown PHASE3
Sep 2024 — Sep 2025 [monthly]

Unknown PHASE3
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE3

Status: Unknown Status → Unknown
Jan 2021 — Jul 2024 [monthly]

Unknown Status PHASE3
Oct 2020 — Jan 2021 [monthly]

Unknown Status PHASE3

Status: Recruiting → Unknown Status

▶ Show 1 earlier version

Oct 2018 — Oct 2020 [monthly]

Recruiting PHASE3

First recorded

Jul 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Develco Pharma Schweiz AG

Data source: Develco Pharma Schweiz AG

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aberdeen, United Kingdom , Addlestone, United Kingdom , Amadora, Portugal , Aveiro, Portugal , Bad Honnef, Germany , Bad Pyrmont, Germany , Banská Bystrica, Slovakia , Barcelona, Spain , Belfast, United Kingdom , Belgrade, Serbia and 94 more locations