deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT03690141

An Open-label Study of the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer

A Phase 2 Non-randomized Open-label Study Examining the Effect of Tomivosertib (eFT508) in Patients With Advanced Castrate-resistant Prostate Cancer (CRPC)

Sponsor: Effector Therapeutics

Interventions eFT508
Updated 11 times since 2018 Last updated: Jun 18, 2024 Started: Nov 27, 2018 Primary completion: Apr 27, 2020 Completion: Apr 27, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated early due to a lack of efficacy.

This PHASE2 trial investigates Castrate-resistant Prostate Cancer (CRPC) and is currently terminated or withdrawn. Effector Therapeutics leads this study, which shows 11 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshotRecruiting~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshotRecruiting~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshotRecruiting~Feb 2019 – ~Aug 2019 · 6 months · monthly snapshotRecruiting~Aug 2019 – ~Jan 2020 · 5 months · monthly snapshotActive Not Recruiting~Jan 2020 – ~May 2020 · 4 months · monthly snapshotActive Not Recruiting~May 2020 – ~Jan 2021 · 8 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. May 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. Jan 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2

  2. Aug 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Feb 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  4. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  5. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  6. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Effector Therapeutics
Data source: Effector Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .