deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT03258398

A Study to Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

A Phase 2, Open-Label, Randomized, Non-Comparative Study With Preliminary Dose Finding to Evaluate eFT508 Monotherapy or eFT508 in Combination With Avelumab in Subjects With Microsatellite Stable Relapsed or Refractory Colorectal Cancer

Sponsor: Effector Therapeutics

Interventions Avelumab eFT508
Updated 12 times since 2017 Last updated: Jul 16, 2019 Started: Sep 18, 2017 Primary completion: Mar 26, 2019 Completion: May 13, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03258398, this PHASE2 trial focuses on Microsatellite Stable Relapsed or Refractory Colorectal Cancer and remains completed. Sponsored by Effector Therapeutics, it has been updated 12 times since 2017, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Sep 2017 – ~Oct 2017 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2017 – ~Dec 2017 · 2 months · monthly snapshotRecruiting~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotRecruiting~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotRecruiting~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshotRecruiting~Sep 2018 – ~Dec 2018 · 3 months · monthly snapshotActive Not Recruiting~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshotActive Not Recruiting~Jan 2019 – ~Aug 2019 · 7 months · monthly snapshotActive Not Recruiting~Aug 2019 – ~Jan 2021 · 17 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Aug 2019 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Jan 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE2

Show 7 earlier versions
  1. Dec 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  4. Jun 2018 — Aug 2018 [monthly]

    Recruiting PHASE2

  5. Dec 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

  6. Oct 2017 — Dec 2017 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Sep 2017 — Oct 2017 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Effector Therapeutics
  • Merck KGaA, Darmstadt, Germany
  • Pfizer
Data source: Effector Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .