deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 11-arm NCT04092673

Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies (Zotatifin)

A Phase 1-2 Dose-Escalation and Cohort-Expansion Study of Intravenous Zotatifin (eFT226) in Subjects With Selected Advanced Solid Tumor Malignancies

Sponsor: Effector Therapeutics

Updated 17 times since 2019 Last updated: May 20, 2024 Started: Oct 25, 2019 Primary completion: Dec 31, 2024 Completion: Mar 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Solid Tumor, Adult, this trial is actively recruiting participants. The trial is conducted by Effector Therapeutics and has accumulated 17 data snapshots since 2019. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Oct 2019 – ~Jan 2020 · 3 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Feb 2022 · 9 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Dec 2022 · 7 months · monthly snapshot~Dec 2022 – ~Aug 2023 · 8 months · monthly snapshot~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Jan 2024 · 3 months · monthly snapshot~Jan 2024 – ~Jun 2024 · 5 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 23 months · monthly snapshot

Change History

17 versions recorded
  1. Sep 2024 — Present [monthly]

    Recruiting PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jan 2024 — Jun 2024 [monthly]

    Recruiting PHASE1_PHASE2

  5. Oct 2023 — Jan 2024 [monthly]

    Recruiting PHASE1_PHASE2

Show 12 earlier versions
  1. Aug 2023 — Oct 2023 [monthly]

    Recruiting PHASE1_PHASE2

  2. Dec 2022 — Aug 2023 [monthly]

    Recruiting PHASE1_PHASE2

  3. May 2022 — Dec 2022 [monthly]

    Recruiting PHASE1_PHASE2

  4. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE1_PHASE2

  5. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. May 2021 — Feb 2022 [monthly]

    Recruiting PHASE1_PHASE2

  7. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  9. May 2020 — Aug 2020 [monthly]

    Recruiting PHASE1_PHASE2

  10. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  11. Jan 2020 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  12. Oct 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Effector Therapeutics
Data source: Effector Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .