deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT03808558

Phase 2 Study of TVB-2640 in KRAS Non-Small Cell Lung Carcinomas

A Phase 2 Multi-center Pharmacodynamics Study of TVB-2640 in KRAS Mutant Non-small Cell Lung Carcinomas

Sponsor: Cancer Prevention Research Institute of Texas

Conditions KRAS Gene Mutation
Interventions TVB-2640
Updated 16 times since 2019 Last updated: Jan 6, 2026 Started: Sep 11, 2019 Primary completion: Apr 3, 2025 Completion: Dec 1, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on KRAS Gene Mutation, this trial is ongoing. The trial is conducted by Cancer Prevention Research Institute of Texas and has accumulated 16 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Oct 2019 · 5 months · monthly snapshot~Oct 2019 – ~Jan 2021 · 15 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Mar 2022 · 12 months · monthly snapshot~Mar 2022 – ~Jan 2023 · 10 months · monthly snapshot~Jan 2023 – ~Jun 2023 · 5 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Jan 2024 · 4 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2025 · 3 months · monthly snapshot~Jan 2025 – ~Jun 2025 · 5 months · monthly snapshot~Jun 2025 – ~Feb 2026 · 8 months · monthly snapshot~Feb 2026 – present · 7 months · monthly snapshot

Change History

16 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Jan 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Oct 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  5. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

▶ Show 11 earlier versions

  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  2. Jan 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  3. Sep 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  4. Jun 2023 — Sep 2023 [monthly]

    Recruiting PHASE2

  5. Jan 2023 — Jun 2023 [monthly]

    Recruiting PHASE2

  6. Mar 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  7. Mar 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

  8. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  9. Oct 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  10. May 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE2

  11. Feb 2019 — May 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cancer Prevention Research Institute of Texas
  • David E Gerber
  • Gateway for Cancer Research
  • Sagimet Biosciences Inc.
Data source: University of Texas Southwestern Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations