deltatrials
Completed OBSERVATIONAL NCT03986541

AREG, EREG and EGFR: Response to Anti-EGFR Agents in Colorectal Cancer

Association Between Tumour Amphiregulin, Epiregulin and Epidermal Growth Factor Receptor (EGFR) Expression and Response to Anti-EGFR Agents in Colorectal Cancer

Sponsor: Newcastle University

Updated 12 times since 2019 Last updated: May 24, 2024 Started: Sep 23, 2019 Primary completion: Feb 22, 2022 Completion: Jul 22, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates Colorectal Cancer Stage IV and is currently completed. Newcastle University leads this study, which shows 12 recorded versions since 2019 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2019 – ~Apr 2020 · 9 months · monthly snapshotNot Yet Recruiting~Apr 2020 – ~Nov 2020 · 7 months · monthly snapshotSuspended~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotSuspended~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotSuspended~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshotRecruiting~Dec 2021 – ~Mar 2022 · 3 months · monthly snapshotRecruiting~Mar 2022 – ~Mar 2024 · 24 months · monthly snapshotActive Not Recruiting~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshotUnknown Status~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed

  2. Sep 2024 — Sep 2025 [monthly]

    Completed

  3. Jul 2024 — Sep 2024 [monthly]

    Completed

  4. Jun 2024 — Jul 2024 [monthly]

    Completed

    Status: Unknown StatusCompleted

  5. Mar 2024 — Jun 2024 [monthly]

    Unknown Status

    Status: Active Not RecruitingUnknown Status

Show 7 earlier versions
  1. Mar 2022 — Mar 2024 [monthly]

    Active Not Recruiting

    Status: RecruitingActive Not Recruiting

  2. Dec 2021 — Mar 2022 [monthly]

    Recruiting

  3. Oct 2021 — Dec 2021 [monthly]

    Recruiting

    Status: SuspendedRecruiting

  4. Jan 2021 — Oct 2021 [monthly]

    Suspended

  5. Nov 2020 — Jan 2021 [monthly]

    Suspended

  6. Apr 2020 — Nov 2020 [monthly]

    Suspended

    Status: Not Yet RecruitingSuspended

  7. Jul 2019 — Apr 2020 [monthly]

    Not Yet Recruiting

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Newcastle University
  • University of Leeds
  • University of Liverpool
  • University of Manchester
  • University of Nottingham
  • University of Sheffield
Data source: University of Leeds

For direct contact, visit the study record on ClinicalTrials.gov .