deltatrials
Recruiting OBSERVATIONAL NCT04023019

Treatment of Hemophilia A Patients With FVIII Inhibitors (MOTIVATE)

MOdern Treatment of Inhibitor-PositiVe PATiEnts With Haemophilia A - An International Observational Study

Sponsor: Emory University

Conditions Hemophilia A
Interventions Activated prothrombin complex concentrate (aPCC) Emicizumab Nuwiq Octanate Recombinant factor VIIa (rFVIIa) Wilate
Updated 16 times since 2019 Last updated: Aug 28, 2025 Started: Mar 17, 2020 Primary completion: Dec 31, 2028 Completion: Jun 30, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Hemophilia A, this trial is actively recruiting participants. The trial is conducted by Emory University and has accumulated 16 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 11 months · monthly snapshot

Change History

16 versions recorded

  1. Oct 2025 — Present [monthly]

    Recruiting

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting

  3. Sep 2024 — Sep 2025 [monthly]

    Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  5. Sep 2023 — Jul 2024 [monthly]

    Recruiting

▶ Show 11 earlier versions

  1. Sep 2022 — Sep 2023 [monthly]

    Recruiting

  2. Sep 2021 — Sep 2022 [monthly]

    Recruiting

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting

  4. Jul 2020 — Jan 2021 [monthly]

    Recruiting

    Status: Not Yet Recruiting → Recruiting

  5. Jun 2020 — Jul 2020 [monthly]

    Not Yet Recruiting

  6. May 2020 — Jun 2020 [monthly]

    Not Yet Recruiting

  7. Apr 2020 — May 2020 [monthly]

    Not Yet Recruiting

  8. Jan 2020 — Apr 2020 [monthly]

    Not Yet Recruiting

  9. Nov 2019 — Jan 2020 [monthly]

    Not Yet Recruiting

  10. Sep 2019 — Nov 2019 [monthly]

    Not Yet Recruiting

  11. Aug 2019 — Sep 2019 [monthly]

    Not Yet Recruiting

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Emory University
  • Octapharma
Data source: Emory University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations