deltatrials
Completed PHASE4 INTERVENTIONAL 1-arm NCT04084314

Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study (APOLLON)

Sponsor: Novartis Pharmaceuticals

Conditions Migraine Migraine Disorders Migraine Headache
Interventions Erenumab
Updated 28 times since 2019 Last updated: Oct 7, 2024 Started: Sep 30, 2019 Primary completion: Feb 23, 2023 Completion: Mar 13, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Migraine and Migraine Disorders and is currently completed. Novartis Pharmaceuticals leads this study, which shows 28 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Oct 2019 – ~Apr 2020 · 6 months · monthly snapshot~Apr 2020 – ~Jun 2020 · 2 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Jun 2021 · 3 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Nov 2022 · 8 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Mar 2024 · 10 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

28 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Nov 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Sep 2024 — Nov 2024 [monthly]

    Completed PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  5. Mar 2024 — Jul 2024 [monthly]

    Completed PHASE4

▶ Show 23 earlier versions

  1. May 2023 — Mar 2024 [monthly]

    Completed PHASE4

    Status: Active Not Recruiting → Completed

  2. Feb 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE4

  3. Dec 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE4

  4. Nov 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE4

  5. Mar 2022 — Nov 2022 [monthly]

    Active Not Recruiting PHASE4

  6. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE4

  7. Jan 2022 — Feb 2022 [monthly]

    Active Not Recruiting PHASE4

  8. Dec 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE4

  9. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE4

  10. Oct 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  11. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE4

    Status: Active Not Recruiting → Recruiting

  12. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE4

  13. Mar 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE4

  14. Jan 2021 — Mar 2021 [monthly]

    Active Not Recruiting PHASE4

  15. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  16. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE4

  17. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE4

  18. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE4

  19. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE4

  20. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE4

  21. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE4

  22. Apr 2020 — Jun 2020 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  23. Oct 2019 — Apr 2020 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Sep 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Alzenau in Unterfranken, Germany , Bad Homburg, Germany , Bad Honnef, Germany , Bad Saarow, Germany , Bayreuth, Germany , Berlin, Germany , Bielefeld, Germany , Bochum, Germany , Bonn, Germany and 50 more locations