deltatrials
Terminated PHASE1 INTERVENTIONAL 3-arm NCT04274907

A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

A Phase 1b Study of Venetoclax in Combination With Pembrolizumab in Subjects With Previously Untreated NSCLC Whose Tumors Have High PD-L1 Expression

Sponsor: AbbVie

Updated 9 times since 2020 Last updated: Feb 10, 2021 Started: Jun 30, 2020 Primary completion: Feb 2, 2021 Completion: Feb 2, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Company Decision

This PHASE1 trial investigates Cancer and Non Small Cell Lung Cancer and is currently terminated or withdrawn. AbbVie leads this study, which shows 9 recorded versions since 2020 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Mar 2020 – ~Aug 2020 · 5 months · monthly snapshotNot Yet Recruiting~Aug 2020 – ~Dec 2020 · 4 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotSuspended~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotSuspended~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshotSuspended~Mar 2021 – ~Jul 2024 · 40 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Mar 2021 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: SuspendedTerminated

  5. Feb 2021 — Mar 2021 [monthly]

    Suspended PHASE1

Show 4 earlier versions
  1. Jan 2021 — Feb 2021 [monthly]

    Suspended PHASE1

  2. Dec 2020 — Jan 2021 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

  3. Aug 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  4. Mar 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .