deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04534283

A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.

A Phase 2 Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib for Patients Whose Tumors Harbor Pathogenic Alterations in BRAF, RAF1, MEK1/2, ERK1/2, and NF1.

Sponsor: Anita Turk

Updated 12 times since 2020 Last updated: Aug 1, 2024 Started: Oct 5, 2020 Primary completion: Aug 7, 2023 Completion: Aug 7, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of efficacy.

Listed as NCT04534283, this PHASE2 trial focuses on BRAF V600E and Cancer and remains terminated or withdrawn. Sponsored by Anita Turk, it has been updated 12 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshotNot Yet Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotRecruiting~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshotRecruiting~Jan 2022 – ~May 2022 · 4 months · monthly snapshotRecruiting~May 2022 – ~Sep 2022 · 4 months · monthly snapshotRecruiting~Sep 2022 – ~Jan 2023 · 4 months · monthly snapshotRecruiting~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshotRecruiting~Feb 2023 – ~Feb 2024 · 12 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Feb 2024 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  4. Feb 2023 — Feb 2024 [monthly]

    Recruiting PHASE2

  5. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE2

Show 7 earlier versions
  1. Sep 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  2. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2022 — May 2022 [monthly]

    Recruiting PHASE2

  4. Oct 2021 — Jan 2022 [monthly]

    Recruiting PHASE2

  5. Jan 2021 — Oct 2021 [monthly]

    Recruiting PHASE2

  6. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Oct 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Anita Turk
  • Eli Lilly and Company
Data source: Indiana University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations