ACTIV-5 / Big Effect Trial (BET-B) for the Treatment of COVID-19
A Multicenter Platform Trial of Putative Therapeutics for the Treatment of COVID-19 in Hospitalized Adults
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Listed as NCT04583969, this PHASE2 trial focuses on COVID-19 and remains completed. Sponsored by National Institute of Allergy and Infectious Diseases (NIAID), it has been updated 20 times since 2020, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.
Status Flow
Change History
20 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE2
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE2
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Jul 2023 — Jul 2024 [monthly]
Completed PHASE2
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Sep 2022 — Jul 2023 [monthly]
Completed PHASE2
▶ Show 15 earlier versions
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Jul 2022 — Sep 2022 [monthly]
Completed PHASE2
Status: Active Not Recruiting → Completed
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Mar 2022 — Jul 2022 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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Jan 2022 — Mar 2022 [monthly]
Recruiting PHASE2
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Dec 2021 — Jan 2022 [monthly]
Recruiting PHASE2
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Nov 2021 — Dec 2021 [monthly]
Recruiting PHASE2
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Oct 2021 — Nov 2021 [monthly]
Recruiting PHASE2
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Sep 2021 — Oct 2021 [monthly]
Recruiting PHASE2
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Jun 2021 — Sep 2021 [monthly]
Recruiting PHASE2
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May 2021 — Jun 2021 [monthly]
Recruiting PHASE2
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Apr 2021 — May 2021 [monthly]
Recruiting PHASE2
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Mar 2021 — Apr 2021 [monthly]
Recruiting PHASE2
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Feb 2021 — Mar 2021 [monthly]
Recruiting PHASE2
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Jan 2021 — Feb 2021 [monthly]
Recruiting PHASE2
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Dec 2020 — Jan 2021 [monthly]
Recruiting PHASE2
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Nov 2020 — Dec 2020 [monthly]
Recruiting PHASE2
First recorded
Oct 2020
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- National Institute of Allergy and Infectious Diseases (NIAID)
For direct contact, visit the study record on ClinicalTrials.gov .