deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04723394

Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults (TACKLE)

A Phase III Randomized, Double-blind, Placebo-controlled, Multicenter Study to Determine the Safety and Efficacy of AZD7442 for the Treatment of COVID-19 in Non-hospitalized Adults

Sponsor: AstraZeneca

Conditions COVID-19
Interventions AZD7442 Placebo
Updated 13 times since 2021 Last updated: Jun 30, 2023 Started: Jan 28, 2021 Primary completion: Aug 21, 2021 Completion: Oct 19, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04723394, this PHASE3 trial focuses on COVID-19 and remains completed. Sponsored by AstraZeneca, it has been updated 13 times since 2021, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Sep 2021 · 6 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Apr 2022 · 6 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Jan 2023 · 6 months · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Jul 2023 · 5 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 8 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Aug 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jul 2023 — Aug 2023 [monthly]

    Completed PHASE3

Show 8 earlier versions
  1. Feb 2023 — Jul 2023 [monthly]

    Completed PHASE3

  2. Jan 2023 — Feb 2023 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Jul 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE3

  4. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE3

  5. Oct 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  6. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  7. Mar 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  8. Feb 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Jan 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .