deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 3-arm NCT04802876

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors (ACROPOLI)

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors Defined by a Single and Pre-specified Cutoff

Sponsor: Novartis

Updated 8 times since 2021 Last updated: Mar 18, 2025 Started: Apr 12, 2021 Primary completion: Sep 30, 2025 Completion: Mar 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04802876, this PHASE2 trial focuses on Anal Carcinoma and Carcinoma of Unknown Primary and remains ongoing. Sponsored by Novartis, it has been updated 8 times since 2021, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Nov 2022 · 14 months · monthly snapshotRecruiting~Nov 2022 – ~Aug 2023 · 9 months · monthly snapshotActive Not Recruiting~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotRecruiting~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshotActive Not Recruiting~Apr 2025 – present · 17 months · monthly snapshotActive Not Recruiting

Change History

8 versions recorded
  1. Apr 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Mar 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  5. Aug 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

    Status: Active Not RecruitingRecruiting

Show 3 earlier versions
  1. Nov 2022 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Sep 2021 — Nov 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Apr 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis
  • SOLTI Breast Cancer Research Group
Data source: SOLTI Breast Cancer Research Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations