deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT05082974

Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Laser-assisted in Situ Keratomileusis (LASIK)

A Randomized, Controlled, Double-Masked, Two-Arm Investigator-Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease in Subjects Following Laser-assisted in Situ Keratomileusis (LASIK)

Sponsor: Vance Thompson Vision ND

Updated 5 times since 2021 Last updated: Jun 8, 2023 Started: Oct 20, 2021 Primary completion: Aug 3, 2022 Completion: Aug 3, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05082974, this PHASE3 trial focuses on Dry Eye Disease and remains completed. Sponsored by Vance Thompson Vision ND, it has been updated 5 times since 2021, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Nov 2021 – ~Jul 2023 · 20 months · monthly snapshotNot Yet Recruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

5 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jul 2023 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Not Yet RecruitingCompleted

  5. Nov 2021 — Jul 2023 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Oct 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Vance Thompson Vision ND
Data source: Vance Thompson Vision ND

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations