deltatrials
Terminated PHASE3 INTERVENTIONAL 3-arm NCT05813288

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) (EXHALE-3)

A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma

Sponsor: Areteia Therapeutics

Updated 16 times since 2023 Last updated: Dec 10, 2025 Started: Mar 27, 2023 Primary completion: Dec 8, 2025 Completion: Dec 8, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Program stopped due to the benefit risk profile no longer supports further development in the intended patient population.

Other terminated trials from Areteia Therapeutics

More terminations from Areteia Therapeutics

Listed as NCT05813288, this PHASE3 trial focuses on Asthma and Asthma; Eosinophilic and remains terminated or withdrawn. Sponsored by Areteia Therapeutics, it has been updated 16 times since 2023, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Sep 2023 · 2 months · monthly snapshot~Sep 2023 – ~Nov 2023 · 2 months · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Mar 2024 · 3 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotRecruiting~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshotTerminated

Change History

16 versions recorded
  1. Jan 2026 — Present [monthly]

    Terminated PHASE3

    Status: Active Not RecruitingTerminated

  2. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  3. Sep 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

  4. Jul 2025 — Sep 2025 [monthly]

    Recruiting PHASE3

  5. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE3

Show 11 earlier versions
  1. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE3

  2. Mar 2025 — May 2025 [monthly]

    Recruiting PHASE3

  3. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  5. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE3

  6. Dec 2023 — Mar 2024 [monthly]

    Recruiting PHASE3

  7. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

  8. Sep 2023 — Nov 2023 [monthly]

    Recruiting PHASE3

  9. Jul 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  10. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  11. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

    First recorded

Mar 2023

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Areteia Therapeutics
Data source: Areteia Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .