deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 3-arm NCT05960240

Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

A Double-Blind, Randomized, Placebo-Controlled, Single and Multiple Dose Study Evaluating the Safety, Tolerability, PK and PD of AB-101, an Oral PD-L1 Inhibitor, in Healthy Subjects and Subjects With Chronic HBV Infection.

Sponsor: Arbutus Biopharma Corporation

Updated 7 times since 2023 Last updated: Jul 16, 2025 Started: Aug 30, 2023 Primary completion: Jan 31, 2026 Completion: Apr 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05960240, this PHASE1 trial focuses on Chronic Hepatitis b and remains ongoing. Sponsored by Arbutus Biopharma Corporation, it has been updated 7 times since 2023, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Aug 2023 – ~Mar 2024 · 7 months · monthly snapshotNot Yet Recruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotRecruiting~Feb 2025 – ~Aug 2025 · 6 months · monthly snapshotRecruiting~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 8 months · monthly snapshotActive Not Recruiting

Change History

7 versions recorded
  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Feb 2025 — Aug 2025 [monthly]

    Recruiting PHASE1

  4. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE1

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

Show 2 earlier versions
  1. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  2. Aug 2023 — Mar 2024 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Arbutus Biopharma Corporation
Data source: Arbutus Biopharma Corporation

For direct contact, visit the study record on ClinicalTrials.gov .