deltatrials
Recruiting PHASE2/PHASE3 INTERVENTIONAL 3-arm NCT06647498

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation (DIAN-TU-002)

A Phase II/III Multicenter Randomized, Double-Blind, Placebo-Controlled, Two-Stage Adaptive Design, Platform Trial of Investigational Treatments for Primary Prevention of Disease Progression in Dominantly Inherited Alzheimer's Disease

Sponsor: Alzheimer's Association

Updated 6 times since 2024 Last updated: Feb 11, 2026 Started: Nov 22, 2024 Primary completion: Mar 31, 2034 Completion: Aug 31, 2034
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06647498, this PHASE2/PHASE3 trial focuses on Alzheimers Disease and Alzheimers Disease, Familial and remains actively recruiting participants. Sponsored by Alzheimer's Association, it has been updated 6 times since 2024, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshotNot Yet Recruiting~Dec 2024 – ~May 2025 · 5 months · monthly snapshotRecruiting~May 2025 – ~Sep 2025 · 4 months · monthly snapshotRecruiting~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshotRecruiting~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshotRecruiting~Feb 2026 – present · 4 months · monthly snapshotRecruiting

Change History

6 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE2/PHASE3

  2. Dec 2025 — Feb 2026 [monthly]

    Recruiting PHASE2/PHASE3

  3. Sep 2025 — Dec 2025 [monthly]

    Recruiting PHASE2/PHASE3

  4. May 2025 — Sep 2025 [monthly]

    Recruiting PHASE2/PHASE3

  5. Dec 2024 — May 2025 [monthly]

    Recruiting PHASE2/PHASE3

    Status: Not Yet RecruitingRecruiting

Show 1 earlier version
  1. Nov 2024 — Dec 2024 [monthly]

    Not Yet Recruiting PHASE2/PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Alzheimer's Association
  • Eli Lilly and Company
  • GHR Foundation
  • National Institute on Aging (NIA)
  • Private Donors
  • Washington University School of Medicine
Data source: Washington University School of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .