deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT06747273

Study to Evaluate the Safety, Tolerability, and Efficacy of SRP-9004 Administered by Systemic Infusion in Limb Girdle Muscular Dystrophy Type 2D/R3 Participants in the United States (DISCOVERY)

A Phase 1b, Multicenter, Single Dose Gene Transfer Study to Evaluate the Safety, Tolerability, and Efficacy of SRP-9004 Administered by Systemic Infusion in Limb Girdle Muscular Dystrophy Type 2D/R3 Subjects in the United States

Sponsor: Sarepta Therapeutics, Inc.

Interventions SRP-9004
Updated 5 times since 2025 Last updated: Aug 27, 2025 Started: Jan 9, 2025 Primary completion: Jun 18, 2025 Completion: Jun 18, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study is being terminated due to a business decision.

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This PHASE1 trial investigates Limb Girdle Muscular Dystrophy and Limb Girdle Muscular Dystrophy Type 2D/R3 and is currently terminated or withdrawn. Sarepta Therapeutics, Inc. leads this study, which shows 5 recorded versions since 2025 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2025 – ~Mar 2025 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Oct 2025 · 5 months · monthly snapshotActive Not Recruiting~Oct 2025 – present · 9 months · monthly snapshotTerminated

Change History

5 versions recorded
  1. Oct 2025 — Present [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  2. May 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: Enrolling By InvitationActive Not Recruiting

  3. Apr 2025 — May 2025 [monthly]

    Enrolling By Invitation PHASE1

  4. Mar 2025 — Apr 2025 [monthly]

    Enrolling By Invitation PHASE1

    Status: Not Yet RecruitingEnrolling By Invitation

  5. Jan 2025 — Mar 2025 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sarepta Therapeutics, Inc.
Data source: Sarepta Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .