deltatrials
Recruiting PHASE2 INTERVENTIONAL 2-arm NCT06814145

Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023) (HARMONIZE)

A Phase 2, Multicenter, Double-blind, Extension Study to Evaluate the Effects of Sotatercept for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) Due to Heart Failure With Preserved Ejection Fraction (HFpEF)

Sponsor: Merck Sharp & Dohme LLC

Interventions Sotatercept
Updated 11 times since 2025 Last updated: Mar 5, 2026 Started: Apr 16, 2025 Primary completion: Mar 30, 2029 Completion: Mar 30, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT06814145, this PHASE2 trial focuses on Hypertension, Pulmonary and remains actively recruiting participants. Sponsored by Merck Sharp & Dohme LLC, it has been updated 11 times since 2025, reflecting substantial change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshotNot Yet Recruiting~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 6 months · monthly snapshotRecruiting

Change History

11 versions recorded
  1. Mar 2026 — Present [monthly]

    Recruiting PHASE2

  2. Feb 2026 — Mar 2026 [monthly]

    Recruiting PHASE2

  3. Jan 2026 — Feb 2026 [monthly]

    Recruiting PHASE2

  4. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

  5. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE2

Show 6 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE2

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  4. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE2

  5. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Mar 2025 — Jun 2025 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .