deltatrials
Recruiting PHASE3 INTERVENTIONAL 2-arm NCT07044336

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4 Selected Advanced/Metastatic Endometrial Cancer Who Progressed On or After Platinum Based Chemotherapy and Anti-PD-1/Anti-PD-L1 Therapy (Bluestar-Endometrial01)

Sponsor: AstraZeneca

Updated 6 times since 2025 Last updated: Mar 4, 2026 Started: Aug 1, 2025 Primary completion: Jan 20, 2028 Completion: Jul 17, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Endometrial Cancer and Malignant Solid Tumour and is currently actively recruiting participants. AstraZeneca leads this study, which shows 6 recorded versions since 2025 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jul 2025 – ~Sep 2025 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Dec 2025 · 2 months · monthly snapshotRecruiting~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshotRecruiting~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshotRecruiting

Change History

6 versions recorded
  1. Mar 2026 — Present [monthly]

    Recruiting PHASE3

  2. Feb 2026 — Mar 2026 [monthly]

    Recruiting PHASE3

  3. Dec 2025 — Feb 2026 [monthly]

    Recruiting PHASE3

  4. Oct 2025 — Dec 2025 [monthly]

    Recruiting PHASE3

  5. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

Show 1 earlier version
  1. Jul 2025 — Sep 2025 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .