Completed PHASE1 INTERVENTIONAL 1-arm NCT00003141

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

A Pilot Study of Intensive Chemotherapy With Peripheral Stem Cell Support for Infants With Malignant Brain Tumors

Sponsor: Children's Oncology Group

Conditions Brain Tumors Central Nervous System Tumors Neuroblastoma Sarcoma

Interventions carboplatin cisplatin conventional surgery cyclophosphamide etoposide filgrastim peripheral blood stem cell transplantation thiotepa vincristine sulfate

Updated 7 times since 2017 Last updated: Mar 27, 2014 Started: Mar 31, 1998 Primary completion: Dec 31, 2007 Completion: Oct 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Brain Tumors and Central Nervous System Tumors and is currently completed. Children's Oncology Group leads this study, which shows 7 recorded versions since 1998 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE1
Sep 2024 — Sep 2025 [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE1
Jan 2017 — Feb 2017 [monthly]

Completed PHASE1

First recorded

Mar 1998

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Children's Oncology Group
National Cancer Institute (NCI)

Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Amarillo, United States , Ann Arbor, United States , Atlanta, United States , Augusta, United States , Aurora, United States , Chapel Hill, United States , Chicago, United States , Cincinnati, United States , Cleveland, United States and 50 more locations