deltatrials
Completed PHASE3 NCT00002944

Combination Chemotherapy in Treating Children With Progressive Brain Tumors

Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than Ten Years Old

Sponsor: Children's Oncology Group

Conditions Brain Tumors Central Nervous System Tumors
Interventions carboplatin lomustine procarbazine hydrochloride thioguanine vincristine sulfate
Updated 7 times since 2017 Last updated: Sep 6, 2013 Started: Apr 30, 1997 Primary completion: Feb 28, 2006 Completion: Apr 30, 2012

A PHASE3 clinical study on Brain Tumors and Central Nervous System Tumors, this trial is completed. The trial is conducted by Children's Oncology Group and has accumulated 7 data snapshots since 1997. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 2 earlier versions

  1. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  2. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Apr 1997

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Oncology Group
  • National Cancer Institute (NCI)
Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States, Albany, United States, Albuquerque, United States, Alexandria, United States, Amarillo, United States, Ann Arbor, United States, Atlanta, United States, Auckland, New Zealand, Augusta, United States, Aurora, United States and 153 more location s