deltatrials
Completed PHASE1 NCT00003935

Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Treatment of Children With Diffuse Intrinsic Brain Stem Glioma With Standard Dose Irradiation and Vincristine Plus Oral VP-16, A POG Pilot Study

Sponsor: Children's Oncology Group

Conditions Brain Tumors Central Nervous System Tumors
Interventions etoposide radiation therapy vincristine sulfate
Updated 6 times since 2017 Last updated: Jul 25, 2014 Started: Sep 30, 1999 Primary completion: Oct 31, 2003 Completion: Mar 31, 2007

Listed as NCT00003935, this PHASE1 trial focuses on Brain Tumors and Central Nervous System Tumors and remains completed. Sponsored by Children's Oncology Group, it has been updated 6 times since 1999, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE1

▶ Show 1 earlier version

  1. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE1

    First recorded

Sep 1999

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Oncology Group
  • National Cancer Institute (NCI)
Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States, Asheville, United States, Atlanta, United States, Baltimore, United States, Bangor, United States, Bern, Switzerland, Birmingham, United States, Boston, United States, Buffalo, United States, Burlington, United States and 75 more location s