deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT00044083

Clinical Trial of Tolcapone for Cognition in Schizophrenia

Randomized, Double-Blinded, Placebo Controlled Study of the Effects of Tolcapone and Entacapone on Cognitive Function in Patients With Schizophrenia and Normal Controls Based on COMT Genotype

Sponsor: National Institute of Mental Health (NIMH)

Conditions Schizophrenia
Interventions Placebo Tolcapone
Updated 9 times since 2017 Last updated: Aug 22, 2018 Started: Aug 31, 2002 Primary completion: Dec 31, 2015 Completion: Dec 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Scientific Director request to use resources for other studies

Other terminated trials from National Institute of Mental Health (NIMH)

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Other Schizophrenia trials with similar outcome

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A PHASE2 clinical study on Schizophrenia, this trial is terminated or withdrawn. The trial is conducted by National Institute of Mental Health (NIMH) and has accumulated 9 data snapshots since 2002. Psychiatric clinical trials are essential for establishing evidence-based treatment standards.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotCompleted~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshotTerminated~Oct 2018 – ~Jan 2021 · 27 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

9 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE2

  5. Oct 2018 — Jan 2021 [monthly]

    Terminated PHASE2

▶ Show 4 earlier versions

  1. Aug 2018 — Oct 2018 [monthly]

    Terminated PHASE2

    Status: Completed → Terminated

  2. Jun 2018 — Aug 2018 [monthly]

    Completed PHASE2

  3. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

  4. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Aug 2002

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Institute of Mental Health (NIMH)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations