Completed PHASE3 INTERVENTIONAL 2-arm NCT00377156

Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases

Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients With One to Three Cerebral Metastases

Sponsor: Alliance for Clinical Trials in Oncology

Conditions Breast Cancer Cognitive/Functional Effects Lung Cancer Metastatic Cancer Prostate Cancer

Interventions radiation therapy stereotactic radiosurgery

Updated 10 times since 2017 Last updated: Sep 14, 2022 Started: Jul 31, 2006 Primary completion: Oct 31, 2014 Completion: Dec 15, 2019

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00377156, this PHASE3 trial focuses on Breast Cancer and Cognitive/Functional Effects and remains completed. Sponsored by Alliance for Clinical Trials in Oncology, it has been updated 10 times since 2006, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

10 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Sep 2022 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Sep 2022 [monthly]

Completed PHASE3
Mar 2020 — Jan 2021 [monthly]

Completed PHASE3

Status: Active Not Recruiting → Completed

▶ Show 5 earlier versions

Mar 2019 — Mar 2020 [monthly]

Active Not Recruiting PHASE3
Jun 2018 — Mar 2019 [monthly]

Active Not Recruiting PHASE3
Sep 2017 — Jun 2018 [monthly]

Active Not Recruiting PHASE3
Feb 2017 — Sep 2017 [monthly]

Active Not Recruiting PHASE3
Jan 2017 — Feb 2017 [monthly]

Active Not Recruiting PHASE3

First recorded

Jul 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Data source: Alliance for Clinical Trials in Oncology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Arlington Heights, United States , Atlanta, United States , Aurora, United States , Billings, United States , Bismarck, United States , Boise, United States , Calgary, Canada , Cape Girardeau, United States , Charlotte, United States and 47 more locations