deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT01111825

Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer

A Phase I/II Trial of Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer

Sponsor: Puma Biotechnology, Inc.

Conditions Breast Cancer
Updated 8 times since 2017 Last updated: Aug 29, 2018 Started: Apr 30, 2010 Primary completion: Jul 31, 2016 Completion: Jul 31, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Breast Cancer, this trial is completed. The trial is conducted by Puma Biotechnology, Inc. and has accumulated 8 data snapshots since 2010. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Dec 2017 · 10 months · monthly snapshotCompleted~Dec 2017 – ~Jun 2018 · 6 months · monthly snapshotCompleted~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshotCompleted~Oct 2018 – ~Jan 2021 · 27 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Oct 2018 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

  5. Jun 2018 — Oct 2018 [monthly]

    Completed PHASE1_PHASE2

Show 3 earlier versions
  1. Dec 2017 — Jun 2018 [monthly]

    Completed PHASE1_PHASE2

  2. Feb 2017 — Dec 2017 [monthly]

    Completed PHASE1_PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE1_PHASE2

    First recorded

Apr 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Puma Biotechnology, Inc.
Data source: Puma Biotechnology, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .