deltatrials
Terminated PHASE1 INTERVENTIONAL 4-arm NCT02058407

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects

A Randomised, Double-blind (Sponsor Unblind), Placebo-controlled, Two Part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects

Sponsor: GlaxoSmithKline

Conditions Bronchiectasis
Updated 11 times since 2017 Last updated: Sep 11, 2018 Started: Jan 28, 2014 Primary completion: Oct 31, 2014 Completion: Oct 31, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Drug related AEs observed upon repeat dosing that with longer treatment duration could become worse. Required action on some biomarkers not observed.

Listed as NCT02058407, this PHASE1 trial focuses on Bronchiectasis and remains terminated or withdrawn. Sponsored by GlaxoSmithKline, it has been updated 11 times since 2014, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Jul 2017 · 6 months · monthly snapshotTerminated~Jul 2017 – ~Aug 2017 · 31 days · monthly snapshotTerminated~Aug 2017 – ~May 2018 · 9 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshotTerminated~Oct 2018 – ~Nov 2020 · 25 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE1

  4. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE1

  5. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE1

Show 6 earlier versions
  1. Oct 2018 — Nov 2020 [monthly]

    Terminated PHASE1

  2. Jun 2018 — Oct 2018 [monthly]

    Terminated PHASE1

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE1

  4. Aug 2017 — May 2018 [monthly]

    Terminated PHASE1

  5. Jul 2017 — Aug 2017 [monthly]

    Terminated PHASE1

  6. Jan 2017 — Jul 2017 [monthly]

    Terminated PHASE1

    First recorded

Jan 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations