Unknown PHASE3 INTERVENTIONAL 2-arm NCT02773524

A Study of Regorafenib in Refractory Advanced Gastro-Oesophageal Cancer (INTEGRATEIIa)

A Randomised Phase III Double-Blind Placebo-Controlled Study of Regorafenib in Refractory Advanced Gastro-Oesophageal Cancer (AGOC)

Sponsor: Academic and Community Cancer Research United

Conditions Gastro-Oesophageal Cancer

Interventions Placebo Regorafenib

Updated 11 times since 2017 Last updated: Jan 11, 2022 Started: Nov 30, 2016 Primary completion: Jan 31, 2022 Completion: Dec 31, 2022

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Gastro-Oesophageal Cancer and is currently ongoing. Academic and Community Cancer Research United leads this study, which shows 11 recorded versions since 2016 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

11 versions recorded

Sep 2025 — Present [monthly]

Unknown PHASE3
Sep 2024 — Sep 2025 [monthly]

Unknown PHASE3
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE3

Status: Unknown Status → Unknown
Feb 2024 — Jul 2024 [monthly]

Unknown Status PHASE3

Status: Active Not Recruiting → Unknown Status
Feb 2022 — Feb 2024 [monthly]

Active Not Recruiting PHASE3

Status: Recruiting → Active Not Recruiting

▶ Show 6 earlier versions

Jun 2021 — Feb 2022 [monthly]

Recruiting PHASE3
Jan 2021 — Jun 2021 [monthly]

Recruiting PHASE3
May 2019 — Jan 2021 [monthly]

Recruiting PHASE3
Nov 2018 — May 2019 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Jun 2018 — Nov 2018 [monthly]

Not Yet Recruiting PHASE3
Jan 2017 — Jun 2018 [monthly]

Not Yet Recruiting PHASE3

First recorded

Nov 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Academic and Community Cancer Research United
Australasian Gastro-Intestinal Trials Group
Canadian Cancer Trials Group
National Health and Medical Research Council, Australia

Data source: Australasian Gastro-Intestinal Trials Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albury, Australia , Anyang, South Korea , Ashford, Australia , Auckland, New Zealand , Bedford Park, Australia , Busan, South Korea , Canberra, Australia , Charlottetown, Canada , Chiba, Japan , Clayton, Australia and 38 more locations