deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03371017

A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer (IMpassion132)

A Phase III, Randomised, Double-Blind, Placebo-Controlled, Multicentre Study Of The Efficacy And Safety Of Atezolizumab Plus Chemotherapy For Patients With Early Relapsing Recurrent (Inoperable Locally Advanced Or Metastatic) Triple-Negative Breast Cancer

Sponsor: Hoffmann-La Roche

Updated 67 times since 2017 Last updated: Oct 29, 2025 Started: Jan 11, 2018 Primary completion: Oct 23, 2024 Completion: Oct 23, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Triple Negative Breast Neoplasms, this trial is completed. The trial is conducted by Hoffmann-La Roche and has accumulated 67 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Jun 2018 · 5 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Oct 2019 · 4 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Dec 2023 · 3 months · monthly snapshot~Dec 2023 – ~Mar 2024 · 3 months · monthly snapshot~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Sep 2025 · 9 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 5 months · monthly snapshot

Change History

67 versions recorded
  1. Dec 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2025 — Dec 2025 [monthly]

    Completed PHASE3

  3. Dec 2024 — Sep 2025 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  4. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

Show 62 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

  2. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  3. Mar 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Dec 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2023 — Dec 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  6. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  7. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  8. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE3

  9. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

  10. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  11. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  12. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  13. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE3

  14. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  15. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  16. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  17. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  18. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  19. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  20. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  21. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  22. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  23. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  24. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  25. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  26. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  27. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  28. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  29. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  30. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  31. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  32. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  33. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  34. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  35. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  36. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  37. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  38. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  39. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  40. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

  41. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  42. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE3

  43. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  44. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  45. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  46. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  47. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  48. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  49. Jun 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  50. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  51. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  52. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  53. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  54. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  55. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  56. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  57. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

  58. Aug 2018 — Sep 2018 [monthly]

    Recruiting PHASE3

  59. Jul 2018 — Aug 2018 [monthly]

    Recruiting PHASE3

  60. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  61. Jan 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  62. Dec 2017 — Jan 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .