deltatrials
Terminated OBSERVATIONAL NCT04197453

The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS) (cvMOBIUS)

Sponsor: Amgen

Conditions ASCVD
Updated 17 times since 2020 Last updated: Oct 8, 2021 Started: Dec 6, 2019 Primary completion: Dec 21, 2020 Completion: Dec 21, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor decision

Other terminated trials from Amgen

See all terminations from Amgen

This observational or N/A phase trial investigates ASCVD and is currently terminated or withdrawn. Amgen leads this study, which shows 17 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Nov 2021 · 9 months · monthly snapshot~Nov 2021 – ~Jul 2024 · 32 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

17 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated

  4. Nov 2021 — Jul 2024 [monthly]

    Terminated

  5. Feb 2021 — Nov 2021 [monthly]

    Terminated

    Status: Recruiting → Terminated

▶ Show 12 earlier versions

  1. Jan 2021 — Feb 2021 [monthly]

    Recruiting

  2. Dec 2020 — Jan 2021 [monthly]

    Recruiting

  3. Oct 2020 — Dec 2020 [monthly]

    Recruiting

  4. Sep 2020 — Oct 2020 [monthly]

    Recruiting

  5. Aug 2020 — Sep 2020 [monthly]

    Recruiting

  6. Jul 2020 — Aug 2020 [monthly]

    Recruiting

  7. Jun 2020 — Jul 2020 [monthly]

    Recruiting

  8. May 2020 — Jun 2020 [monthly]

    Recruiting

  9. Apr 2020 — May 2020 [monthly]

    Recruiting

  10. Mar 2020 — Apr 2020 [monthly]

    Recruiting

  11. Feb 2020 — Mar 2020 [monthly]

    Recruiting

  12. Jan 2020 — Feb 2020 [monthly]

    Recruiting

    First recorded

Dec 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
  • Duke Clinical Research Institute
Data source: Amgen

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Altoona, United States , Anderson, United States , Arlington Heights, United States , Atlanta, United States , Austin, United States , Bay City, United States , Beverly Hills, United States , Birmingham, United States , Bossier City, United States and 129 more locations