deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT04341311

Phase I Study of Marizomib + Panobinostat for Children With DIPG (DIPG)

Phase 1 Trial of Marizomib Alone and in Combination With Panobinostat for Children With Diffuse Intrinsic Pontine Glioma

Sponsor: Celgene

Updated 13 times since 2020 Last updated: Feb 14, 2024 Started: Aug 10, 2020 Primary completion: Feb 14, 2024 Completion: Feb 14, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Withdrawal of support from BMS

Listed as NCT04341311, this PHASE1 trial focuses on Diffuse Glioma and Diffuse Intrinsic Pontine Glioma and remains terminated or withdrawn. Sponsored by Celgene, it has been updated 13 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Oct 2021 · 4 months · monthly snapshot~Oct 2021 – ~Jun 2022 · 8 months · monthly snapshot~Jun 2022 – ~Jun 2023 · 12 months · monthly snapshot~Jun 2023 – ~Feb 2024 · 8 months · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Mar 2024 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  4. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Jun 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE1

Show 8 earlier versions
  1. Jun 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

  2. Oct 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Jun 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  5. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  6. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  7. Aug 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE1

  8. May 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Celgene
  • Dana-Farber Cancer Institute
  • Secura Bio, Inc.
Data source: Dana-Farber Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations