deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT05057247

Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

A Phase II Study of Duvelisib Plus Docetaxel in PD-1 Inhibitor Experienced Patients With Incurable Head and Neck Squamous Cell Carcinoma

Sponsor: Glenn J. Hanna

Updated 11 times since 2021 Last updated: Oct 28, 2025 Started: Oct 14, 2021 Primary completion: Oct 1, 2023 Completion: Jun 13, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Advanced Head and Neck Cancer and Advanced Head and Neck Squamous Cell Carcinoma and is currently completed. Glenn J. Hanna leads this study, which shows 11 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Oct 2021 – ~Mar 2022 · 5 months · monthly snapshotNot Yet Recruiting~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshotRecruiting~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshotRecruiting~Feb 2023 – ~Aug 2023 · 6 months · monthly snapshotRecruiting~Aug 2023 – ~Oct 2023 · 2 months · monthly snapshot~Oct 2023 – ~Jan 2024 · 3 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotActive Not Recruiting~Apr 2025 – ~Nov 2025 · 7 months · monthly snapshotActive Not Recruiting~Nov 2025 – present · 8 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Apr 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Apr 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jan 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 6 earlier versions
  1. Oct 2023 — Jan 2024 [monthly]

    Recruiting PHASE2

  2. Aug 2023 — Oct 2023 [monthly]

    Recruiting PHASE2

  3. Feb 2023 — Aug 2023 [monthly]

    Recruiting PHASE2

  4. Sep 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  5. Mar 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Oct 2021 — Mar 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Glenn J. Hanna
  • Secura Bio, Inc.
Data source: Dana-Farber Cancer Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations