A Study to Evaluate Lanraplenib (LANRA) in Combination With Gilteritinib in Participants With FLT3-mutated Relapsed or Refractory Acute Myeloid Leukemia (AML)
A Phase 1b/2 Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of the Selective SYK Inhibitor Lanraplenib (LANRA) in Combination With the FLT3 Inhibitor Gilteritinib, in Patients With FLT3-mutated Relapsed or Refractory AML
Sponsor: Kronos Bio
Terminated
Sponsor decision
Other terminated trials from Kronos Bio
- HGSOC · Phase PHASE1/PHASE2 · Feb 2025
- Nucleophosmin 1-mutated Acute Myeloid Leukemia · Phase PHASE3 · Mar 2023
More terminations from Kronos Bio
A PHASE1/PHASE2 clinical study on Acute Myeloid Leukemia and Refractory Acute Myeloid Leukemia, this trial is terminated or withdrawn. The trial is conducted by Kronos Bio and has accumulated 20 data snapshots since 2022. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
20 versions recorded-
Sep 2024 — Present [monthly]
Terminated PHASE1/PHASE2
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
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May 2024 — Jul 2024 [monthly]
Terminated PHASE1_PHASE2
Status: Active Not Recruiting → Terminated
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Mar 2024 — May 2024 [monthly]
Active Not Recruiting PHASE1_PHASE2
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Jan 2024 — Mar 2024 [monthly]
Active Not Recruiting PHASE1_PHASE2
Status: Recruiting → Active Not Recruiting
▶ Show 15 earlier versions
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Sep 2023 — Jan 2024 [monthly]
Recruiting PHASE1_PHASE2
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Aug 2023 — Sep 2023 [monthly]
Recruiting PHASE1_PHASE2
-
Jun 2023 — Aug 2023 [monthly]
Recruiting PHASE1_PHASE2
-
May 2023 — Jun 2023 [monthly]
Recruiting PHASE1_PHASE2
-
Apr 2023 — May 2023 [monthly]
Recruiting PHASE1_PHASE2
-
Jan 2023 — Apr 2023 [monthly]
Recruiting PHASE1_PHASE2
-
Dec 2022 — Jan 2023 [monthly]
Recruiting PHASE1_PHASE2
-
Nov 2022 — Dec 2022 [monthly]
Recruiting PHASE1_PHASE2
-
Sep 2022 — Nov 2022 [monthly]
Recruiting PHASE1_PHASE2
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Jun 2022 — Sep 2022 [monthly]
Recruiting PHASE1_PHASE2
-
Mar 2022 — Jun 2022 [monthly]
Recruiting PHASE1_PHASE2
-
Feb 2022 — Mar 2022 [monthly]
Recruiting PHASE1_PHASE2
-
Jan 2022 — Feb 2022 [monthly]
Recruiting PHASE1_PHASE2
Status: Not Yet Recruiting → Recruiting
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Dec 2021 — Jan 2022 [monthly]
Not Yet Recruiting PHASE1_PHASE2
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Sep 2021 — Dec 2021 [monthly]
Not Yet Recruiting PHASE1_PHASE2
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Kronos Bio
For direct contact, visit the study record on ClinicalTrials.gov .