deltatrials
Completed PHASE2 INTERVENTIONAL 14-arm NCT05101564

Umbrella Trial of Subtype-Targeted Therapies in ER+/HER2- Breast Cancer

An Umbrella, Randomized, Controlled, Pre Operative Trial Testing Integrative Subtype Targeted Therapeutics in Estrogen Receptor Positive, HER2-Negative Breast Cancer

Sponsor: Effector Therapeutics

Updated 12 times since 2021 Last updated: Jan 23, 2026 Started: Mar 20, 2023 Primary completion: Jun 3, 2024 Completion: Jun 3, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Cancer and ER Positive Breast Cancer, this trial is completed. The trial is conducted by Effector Therapeutics and has accumulated 12 data snapshots since 2023. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshotNot Yet Recruiting~Feb 2022 – ~Jul 2022 · 5 months · monthly snapshotNot Yet Recruiting~Jul 2022 – ~Dec 2022 · 5 months · monthly snapshotNot Yet Recruiting~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshotNot Yet Recruiting~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshotNot Yet Recruiting~Apr 2023 – ~May 2024 · 13 months · monthly snapshotRecruiting~May 2024 – ~Jul 2024 · 2 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotActive Not Recruiting~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotActive Not Recruiting~Aug 2025 – ~Feb 2026 · 6 months · monthly snapshotSuspended~Feb 2026 – present · 5 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE2

    Status: SuspendedCompleted

  2. Aug 2025 — Feb 2026 [monthly]

    Suspended PHASE2

    Status: Active Not RecruitingSuspended

  3. Sep 2024 — Aug 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

Show 7 earlier versions
  1. May 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Apr 2023 — May 2024 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Mar 2023 — Apr 2023 [monthly]

    Not Yet Recruiting PHASE2

  4. Dec 2022 — Mar 2023 [monthly]

    Not Yet Recruiting PHASE2

  5. Jul 2022 — Dec 2022 [monthly]

    Not Yet Recruiting PHASE2

  6. Feb 2022 — Jul 2022 [monthly]

    Not Yet Recruiting PHASE2

  7. Dec 2021 — Feb 2022 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Effector Therapeutics
  • Jennifer Lee Caswell-Jin
  • Novartis Pharmaceuticals
  • United States Department of Defense
Data source: Stanford University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations