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Recruiting OBSERVATIONAL NCT05489705

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) (DISCOVER-HCM)

Deliver Insights in Hypertrophic Cardiomyopathy and Observational Outcomes in Real World: United States and European Prospective Registry Study

Sponsor: Bristol-Myers Squibb

Updated 18 times since 2022 Last updated: Nov 5, 2025 Started: Aug 16, 2022 Primary completion: Aug 17, 2029 Completion: Aug 17, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT05489705, this observational or N/A phase trial focuses on Obstructive Hypertrophic Cardiomyopathy and remains actively recruiting participants. Sponsored by Bristol-Myers Squibb, it has been updated 18 times since 2022, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Mar 2023 · 4 months · monthly snapshot~Mar 2023 – ~Oct 2023 · 7 months · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~May 2024 · 2 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2025 · 3 months · monthly snapshot~Jan 2025 – ~May 2025 · 4 months · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – present · 8 months · monthly snapshot

Change History

18 versions recorded
  1. Dec 2025 — Present [monthly]

    Recruiting

  2. Sep 2025 — Dec 2025 [monthly]

    Recruiting

  3. May 2025 — Sep 2025 [monthly]

    Recruiting

  4. Jan 2025 — May 2025 [monthly]

    Recruiting

  5. Oct 2024 — Jan 2025 [monthly]

    Recruiting

Show 13 earlier versions
  1. Sep 2024 — Oct 2024 [monthly]

    Recruiting

  2. Aug 2024 — Sep 2024 [monthly]

    Recruiting

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting

  4. May 2024 — Jul 2024 [monthly]

    Recruiting

  5. Mar 2024 — May 2024 [monthly]

    Recruiting

  6. Feb 2024 — Mar 2024 [monthly]

    Recruiting

  7. Jan 2024 — Feb 2024 [monthly]

    Recruiting

  8. Dec 2023 — Jan 2024 [monthly]

    Recruiting

  9. Nov 2023 — Dec 2023 [monthly]

    Recruiting

  10. Oct 2023 — Nov 2023 [monthly]

    Recruiting

  11. Mar 2023 — Oct 2023 [monthly]

    Recruiting

  12. Nov 2022 — Mar 2023 [monthly]

    Recruiting

    Status: Not Yet RecruitingRecruiting

  13. Sep 2022 — Nov 2022 [monthly]

    Not Yet Recruiting

    First recorded

Aug 2022

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
Data source: Bristol-Myers Squibb

For direct contact, visit the study record on ClinicalTrials.gov .