deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT02537444

Acalabrutinib (ACP-196) Alone and in Combination With Pembrolizumab in Ovarian Cancer (KEYNOTE191)

A Phase 2 Proof-of-Concept Study of ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Recurrent Ovarian Cancer

Sponsor: Acerta Pharma BV

Conditions Ovarian Cancer
Updated 11 times since 2017 Last updated: Sep 12, 2019 Started: Nov 30, 2015 Primary completion: Jul 31, 2018 Completion: Oct 31, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT02537444, this PHASE2 trial focuses on Ovarian Cancer and remains completed. Sponsored by Acerta Pharma BV, it has been updated 11 times since 2015, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshotActive Not Recruiting~Dec 2018 – ~Oct 2019 · 10 months · monthly snapshotUnknown Status~Oct 2019 – ~Jan 2021 · 15 months · monthly snapshotCompleted~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshotCompleted~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Jun 2022 — Dec 2022 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Jan 2021 — Jun 2022 [monthly]

    Completed PHASE2

  2. Oct 2019 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Unknown StatusCompleted

  3. Dec 2018 — Oct 2019 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

  4. Jun 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Nov 2015

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Acerta Pharma BV
  • Merck Sharp & Dohme LLC
Data source: Acerta Pharma BV

For direct contact, visit the study record on ClinicalTrials.gov .