deltatrials
Terminated PHASE1 INTERVENTIONAL 2-arm NCT04025216

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

A Phase 1 Open-Label, Multi-Center First in Human Study of TnMUC1-Targeted Genetically-Modified Chimeric Antigen Receptor T Cells in Patients With Advanced TnMUC1-Positive Solid Tumors and Multiple Myeloma

Sponsor: Kite, A Gilead Company

Conditions Fallopian Tube Cancer Multiple Myeloma Non-Small Cell Lung Cancer Ovarian Cancer Pancreatic Ductal Adenocarcinoma Triple Negative Breast Cancer
Interventions CART-TnMUC1 Cyclophosphamide Fludarabine
Updated 21 times since 2019 Last updated: Jan 22, 2024 Started: Oct 10, 2019 Primary completion: Dec 2, 2022 Completion: Dec 2, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The sponsor finds the risk/benefit analysis unfavorable and has terminated the study.

Other terminated trials from Kite, A Gilead Company

See all terminations from Kite, A Gilead Company

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Listed as NCT04025216, this PHASE1 trial focuses on Fallopian Tube Cancer and Multiple Myeloma and remains terminated or withdrawn. Sponsored by Kite, A Gilead Company, it has been updated 21 times since 2019, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~Jul 2020 · 3 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~May 2021 · 2 months · monthly snapshot~May 2021 – ~Dec 2021 · 7 months · monthly snapshot~Dec 2021 – ~May 2022 · 5 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~May 2023 · 8 months · monthly snapshot~May 2023 – ~Feb 2024 · 9 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

21 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE1

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  4. Feb 2024 — Jul 2024 [monthly]

    Terminated PHASE1

  5. May 2023 — Feb 2024 [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

▶ Show 16 earlier versions

  1. Sep 2022 — May 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  2. May 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  3. Dec 2021 — May 2022 [monthly]

    Recruiting PHASE1

  4. May 2021 — Dec 2021 [monthly]

    Recruiting PHASE1

  5. Mar 2021 — May 2021 [monthly]

    Recruiting PHASE1

  6. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE1

  7. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  8. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

  9. Sep 2020 — Nov 2020 [monthly]

    Recruiting PHASE1

  10. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE1

  11. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE1

    Status: Active Not Recruiting → Recruiting

  12. Apr 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  13. Jan 2020 — Apr 2020 [monthly]

    Recruiting PHASE1

  14. Nov 2019 — Jan 2020 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  15. Oct 2019 — Nov 2019 [monthly]

    Not Yet Recruiting PHASE1

  16. Aug 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kite, A Gilead Company
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations