deltatrials
Terminated PHASE1 INTERVENTIONAL 6-arm NCT03704298

Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Utomilumab in Adults With Refractory Large B-cell Lymphoma (ZUMA-11)

A Phase 1/2 Multi-center Study Evaluating the Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Utomilumab in Subjects With Relapsed/Refractory Large B-Cell Lymphoma

Sponsor: Kite, A Gilead Company

Conditions Relapsed/Refractory Large B-cell Lymphoma
Interventions Axicabtagene Ciloleucel Cyclophosphamide Fludarabine Utomilumab
Updated 27 times since 2018 Last updated: Jun 26, 2024 Started: Nov 20, 2018 Primary completion: May 7, 2021 Completion: Dec 15, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Development program terminated

Other terminated trials from Kite, A Gilead Company

See all terminations from Kite, A Gilead Company

Other Relapsed/Refractory Large B-cell Lymphoma trials with similar outcome

Browse all Relapsed/Refractory Large B-cell Lymphoma trials

This PHASE1 trial investigates Relapsed/Refractory Large B-cell Lymphoma and is currently terminated or withdrawn. Kite, A Gilead Company leads this study, which shows 27 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~Sep 2019 · 5 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Apr 2020 · 2 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Nov 2021 · 5 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Jan 2023 · 6 months · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

27 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE1

    Status: Active Not Recruiting → Terminated

  4. Jul 2022 — Jan 2023 [monthly]

    Active Not Recruiting PHASE1

  5. Jun 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE1

▶ Show 22 earlier versions

  1. Apr 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

    Phase: PHASE1_PHASE2 → PHASE1

  2. Jan 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Dec 2021 — Jan 2022 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  4. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  5. Jun 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  6. Apr 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: Recruiting → Active Not Recruiting

  7. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE1_PHASE2

  8. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  9. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE1_PHASE2

  10. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE1_PHASE2

  11. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE1_PHASE2

  12. Jun 2020 — Sep 2020 [monthly]

    Recruiting PHASE1_PHASE2

  13. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE1_PHASE2

  14. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1_PHASE2

  15. Feb 2020 — Apr 2020 [monthly]

    Recruiting PHASE1_PHASE2

  16. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE1_PHASE2

  17. Sep 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

  18. Apr 2019 — Sep 2019 [monthly]

    Recruiting PHASE1_PHASE2

  19. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE1_PHASE2

  20. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE1_PHASE2

  21. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet Recruiting → Recruiting

  22. Nov 2018 — Jan 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kite, A Gilead Company
  • Pfizer
Data source: Gilead Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations