deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 1-arm NCT04130997

An Extension Study of Ublituximab in Participants With Relapsing Multiple Sclerosis

An Open Label Extension Study of Ublituximab in Subjects With Relapsing Multiple Sclerosis

Sponsor: TG Therapeutics, Inc.

Conditions Relapsing Multiple Sclerosis (RMS)
Interventions Ublituximab
Updated 68 times since 2019 Last updated: Feb 25, 2026 Started: Nov 18, 2019 Primary completion: May 31, 2032 Completion: May 31, 2032
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Relapsing Multiple Sclerosis (RMS) and is currently ongoing. TG Therapeutics, Inc. leads this study, which shows 68 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

68 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Jan 2026 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  4. Nov 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE3

▶ Show 63 earlier versions

  1. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2025 — Jul 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Apr 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

  6. Mar 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

  7. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

  9. Dec 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

  10. Nov 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE3

  11. Oct 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE3

  12. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE3

  13. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  14. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

  15. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  16. May 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

  17. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE3

    Status: Enrolling By Invitation → Active Not Recruiting

  18. Feb 2024 — Apr 2024 [monthly]

    Enrolling By Invitation PHASE3

  19. Jan 2024 — Feb 2024 [monthly]

    Enrolling By Invitation PHASE3

  20. Dec 2023 — Jan 2024 [monthly]

    Enrolling By Invitation PHASE3

  21. Nov 2023 — Dec 2023 [monthly]

    Enrolling By Invitation PHASE3

  22. Oct 2023 — Nov 2023 [monthly]

    Enrolling By Invitation PHASE3

  23. Sep 2023 — Oct 2023 [monthly]

    Enrolling By Invitation PHASE3

  24. Aug 2023 — Sep 2023 [monthly]

    Enrolling By Invitation PHASE3

  25. Jul 2023 — Aug 2023 [monthly]

    Enrolling By Invitation PHASE3

  26. May 2023 — Jul 2023 [monthly]

    Enrolling By Invitation PHASE3

  27. Apr 2023 — May 2023 [monthly]

    Enrolling By Invitation PHASE3

  28. Mar 2023 — Apr 2023 [monthly]

    Enrolling By Invitation PHASE3

  29. Jan 2023 — Mar 2023 [monthly]

    Enrolling By Invitation PHASE3

  30. Dec 2022 — Jan 2023 [monthly]

    Enrolling By Invitation PHASE3

  31. Nov 2022 — Dec 2022 [monthly]

    Enrolling By Invitation PHASE3

  32. Sep 2022 — Nov 2022 [monthly]

    Enrolling By Invitation PHASE3

  33. Jul 2022 — Sep 2022 [monthly]

    Enrolling By Invitation PHASE3

  34. Jun 2022 — Jul 2022 [monthly]

    Enrolling By Invitation PHASE3

  35. May 2022 — Jun 2022 [monthly]

    Enrolling By Invitation PHASE3

  36. Apr 2022 — May 2022 [monthly]

    Enrolling By Invitation PHASE3

  37. Mar 2022 — Apr 2022 [monthly]

    Enrolling By Invitation PHASE3

  38. Feb 2022 — Mar 2022 [monthly]

    Enrolling By Invitation PHASE3

  39. Jan 2022 — Feb 2022 [monthly]

    Enrolling By Invitation PHASE3

  40. Dec 2021 — Jan 2022 [monthly]

    Enrolling By Invitation PHASE3

  41. Nov 2021 — Dec 2021 [monthly]

    Enrolling By Invitation PHASE3

  42. Oct 2021 — Nov 2021 [monthly]

    Enrolling By Invitation PHASE3

  43. Sep 2021 — Oct 2021 [monthly]

    Enrolling By Invitation PHASE3

  44. Jun 2021 — Sep 2021 [monthly]

    Enrolling By Invitation PHASE3

  45. May 2021 — Jun 2021 [monthly]

    Enrolling By Invitation PHASE3

  46. Apr 2021 — May 2021 [monthly]

    Enrolling By Invitation PHASE3

  47. Mar 2021 — Apr 2021 [monthly]

    Enrolling By Invitation PHASE3

  48. Feb 2021 — Mar 2021 [monthly]

    Enrolling By Invitation PHASE3

  49. Jan 2021 — Feb 2021 [monthly]

    Enrolling By Invitation PHASE3

  50. Dec 2020 — Jan 2021 [monthly]

    Enrolling By Invitation PHASE3

  51. Nov 2020 — Dec 2020 [monthly]

    Enrolling By Invitation PHASE3

  52. Oct 2020 — Nov 2020 [monthly]

    Enrolling By Invitation PHASE3

  53. Sep 2020 — Oct 2020 [monthly]

    Enrolling By Invitation PHASE3

  54. Aug 2020 — Sep 2020 [monthly]

    Enrolling By Invitation PHASE3

  55. Jul 2020 — Aug 2020 [monthly]

    Enrolling By Invitation PHASE3

  56. Jun 2020 — Jul 2020 [monthly]

    Enrolling By Invitation PHASE3

  57. May 2020 — Jun 2020 [monthly]

    Enrolling By Invitation PHASE3

  58. Apr 2020 — May 2020 [monthly]

    Enrolling By Invitation PHASE3

  59. Mar 2020 — Apr 2020 [monthly]

    Enrolling By Invitation PHASE3

  60. Feb 2020 — Mar 2020 [monthly]

    Enrolling By Invitation PHASE3

  61. Jan 2020 — Feb 2020 [monthly]

    Enrolling By Invitation PHASE3

    Status: Not Yet Recruiting → Enrolling By Invitation

  62. Dec 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE3

  63. Nov 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • TG Therapeutics, Inc.
Data source: TG Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Amherst, United States , Arkhangelsk, Russia , Barnaul, Russia , Belgrade, Serbia , Bryansk, Russia , Chelyabinsk, Russia , Cherkasy, Ukraine , Chernihiv, Ukraine , Chernivtsi, Ukraine and 56 more locations