deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 1-arm NCT02191488

ALA-induced PpIX Fluorescence During Brain Tumor Resection

Quantification of ALA-induced PpIX Fluorescence During Brain Tumor Resection

Sponsor: David W. Roberts

Conditions Brain Tumors
Interventions 5-aminolevulinic acid
Updated 14 times since 2017 Last updated: Sep 9, 2025 Started: Jul 31, 2014 Primary completion: Dec 31, 2025 Completion: Dec 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Brain Tumors and is currently ongoing. David W. Roberts leads this study, which shows 14 recorded versions since 2014 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Apr 2018 · 14 months · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~May 2019 · 11 months · monthly snapshot~May 2019 – ~May 2020 · 12 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Jun 2022 · 12 months · monthly snapshot~Jun 2022 – ~Jun 2023 · 12 months · monthly snapshot~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 11 months · monthly snapshot

Change History

14 versions recorded

  1. Oct 2025 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Jun 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

▶ Show 9 earlier versions

  1. Jun 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

  2. Jun 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1

  4. May 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  5. May 2019 — May 2020 [monthly]

    Recruiting PHASE1

  6. Jun 2018 — May 2019 [monthly]

    Recruiting PHASE1

  7. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

  8. Feb 2017 — Apr 2018 [monthly]

    Recruiting PHASE1

  9. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE1

    First recorded

Jul 2014

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • David W. Roberts
  • National Institute of Neurological Disorders and Stroke (NINDS)
Data source: Dartmouth-Hitchcock Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations